Nuria García

Clinical endometritis is defined as purulent or mucopurulent uterine discharge present in the vagina after 21 days postpartum, and it is associated with tissue damage, delayed uterine involution, disruption of endometrial function, and perturbation of ovarian cycles.

The main bacteria associated with clinical endometritis are Escherichia coli, Trueperella pyogenes, Fusobacterium necrophorum, and Prevotella species. Traditionally, intrauterine broad-spectrum antibiotics such as oxytetracycline have been used for treating clinical endometritis. However, this practice increases the risk of antibiotic residue presence in milk after intrauterine infusion, and the emergence of multidrug resistance bacteria.

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