Biotin is a water-soluble vitamin that is synthesized by ruminal bacteria. It is a vital enzyme cofactor involved in several metabolic processes including fat and carbohydrate metabolism, and protein synthesis.
Folic acid or folate is a B-complex vitamin that works as a donor and acceptor of one‐carbon units. Thus, it is involved in the synthesis of nucleic acids (DNA) and amino acids (methionine). The name folic acid is deduced from folium (leaf in Latin), because this vitamin was originally isolated from spinach leaves.